Research Article

Clinical Application of Screening for GJB2 Mutations before Cochlear Implantation in a Heterogeneous Population with High Rate of Autosomal Recessive Nonsyndromic Hearing Loss

Table 4

SAT, SRT, and MCL measurements and gender distribution of patients in the sample. Patients with GJB2 mutations are subcategorized into two columns, based on the presence of 35delG variant. Continuous values are presented as mean ± standard deviation; dichotomous values are presented as frequency (percentage in row). Values pertain to the operated ear only. Unit of measurement: dB.

35delG mutationNon-35delG mutationNo mutation

GenderMale26 (56.5%)8 (50%)74 (53.2%)
Female20 (43.5%)8 (50%)65 (46.8%)

SAT
One month after surgery43.6 ± 3.841.7 ± 2.944.1 ± 5.1
Three months after surgery40.7 ± 5.335.0 ± 0*39.7 ± 4.8

SRT
Six months after surgery40.8 ± 4.543.3 ± 2.939.2 ± 4.7
Twelve months after surgery38.5 ± 4.737.7 ± 7.637.3 ± 4.1

MCL
Six months after surgery71.8 ± 4.075.0 ± 0.0*72.1 ± 4.4
Twelve months after surgery69.7 ± 6.066.7 ± 7.671.5 ± 4.4

Total**4616139

*All measured values were equal, hence a standard deviation equaling zero.
**Not all values presented in the table were available for the total number of subjects in each group.