Mechanistic Roles of Noncoding RNAs in Lung Cancer Biology and Their Clinical Implications

Table 3

Involvement of lncRNAs in lung cancer and technologies used for identification.

lncRNA	Significance	Technology	Source tissue	Reference
Overexpression of MALAT1	Predict metastasis and survival in early-stage NSCLC	Subtractive hybridization method, sequencing and quantitative RT-PCR	Shock frozen primary nonsmall cell lung tumors	[15]
Deregulated expression of BC200	Detectable at significant levels in tumors.; Normal tissue from the same patient was found to be BC200-negative	In situ hybridization	Tumour and normal tissue frozen in liquid nitrogen	[87]
Overexpression of H19	Loss of imprinting in lung adenocarcinoma	RT-PCR	LC tissue and normal lung	[176]