Genetics Research International / 2014 / Article / Tab 3

Research Article

Power Estimation for Gene-Longevity Association Analysis Using Concordant Twins

Table 3

Power estimates for recessive effects using longevity concordant MZ twins.

Relative risk90+95+
100200300500800100200300500800

MAF = 0.05
 0.50.070.150.260.410.150.470.660.870.99
 0.70.050.100.120.060.150.260.38
 0.80.080.100.13
 0.850.070.070.10
 0.90.060.08
 0.950.05
MAF = 0.1
 0.50.250.480.700.880.980.851.001.001.001.00
 0.70.070.130.200.310.470.180.400.570.810.96
 0.80.080.100.120.190.090.130.230.310.52
 0.850.060.080.090.120.110.110.180.30
 0.90.050.050.050.070.070.080.080.15
 0.950.050.060.050.070.08
MAF = 0.2
 0.50.901.001.001.001.001.001.001.001.001.00
 0.70.290.500.680.880.980.750.961.001.001.00
 0.80.130.200.290.450.660.320.550.750.910.98
 0.850.080.120.170.260.380.170.310.400.630.85
 0.90.060.070.100.130.180.080.150.170.260.41
 0.950.050.060.070.060.090.050.090.080.080.12
MAF = 0.5
 0.51.001.001.001.001.001.001.001.001.001.00
 0.70.921.001.001.001.001.001.001.001.001.00
 0.80.510.770.910.991.000.901.001.001.001.00
 0.850.280.470.650.870.970.630.890.981.001.00
 0.90.140.220.310.450.640.260.500.680.870.98
 0.950.060.080.110.140.190.090.160.200.300.46

Power estimates over the lines are acceptable.
bDashes indicate power estimates <0.05.