An Introspective Update on the Influence of miRNAs in Breast Carcinoma and Neuroblastoma Chemoresistance

Table 1

Classification of the different breast cancer subtypes and their most commonly associated molecular features and their related prognosis.

Breast cancer subtype	Molecular features	Clinical outcomes	References
Luminal A	ER+ and/or PR, HER2−	Stage I	[149]
Luminal B	ER+ and/or PR+, HER2+	Stage I (III also reported)	[149, 150]
HER2-enriched	ER− and/or PR−, HER2+	Mostly stage III	[149, 150]
Basal-like subtype or triple-negative	ER− and/or PR−, HER2−, BRCA1	Mostly stage III	[149–151]

ER: estrogen receptor, PR: progesterone receptor, HER: human epidermal growth factor receptor, and BRCA: breast cancer genes; + indicates the presence of the receptor; − indicates the absence of the receptor.