Genetic Variant in the CYP19A1 Gene Associated with Coronary Artery Disease

Table 2

Genotypes and alleles frequencies of rs10046 polymorphism of CYP19A1 gene in patients and controls according to sex.

All participants ()
	Patients ()	Controls ()		OR (95% CI)	value
Genotype
CC, (%)	42 (0.34)	13 (0.20)
CT, (%)	59 (0.48)	32 (0.48)	6.748		0.034
TT, (%)	22 (0.18)	21 (0.32)
Allele
C, %	0.58	0.44		1.771 (1.156–2.175)	0.010
T, %	0.42	0.56
Males ()
	Patients ()	Controls ()		OR (95% CI)	value
Genotype
CC, (%)	28 (0.28)	7 (0.13)
CT, (%)	51 (0.52)	26 (0.50)	6.769		0.034
TT, (%)	20 (0.20)	19 (0.37)
Allele
C, %	0.54	0.38		1.881 (1.160–3.052)	0.010
T, %	0.46	0.62
Females ()
	Patients ()	Controls ()		OR (95% CI)	value
Genotype
CC, (%)	14 (0.58)	6 (0.43)
CT, (%)	8 (0.34)	6 (0.43)	0.915		0.633
TT, (%)	2 (0.08)	2 (0.14)
Allele
C, %	0.75	0.64		1.667; (0.606–4.586)	0.320
T, %	0.25	0.36

OR: odds ratio and CI: confidence interval.