Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster

Figure 2

Three rows by three columns self-organizing map (3 × 3 SOM) for gene expression patterns of clusters. Each cluster is represented by the centroid (average pattern) for genes. The -axis shows the time points (days in the cages). The -axis is the standardized mean log₂ ratios between any other time point and time point 0 and indicates average fold change. The number of genes within each cluster is represented by the whole number in the top center of the square. For example, in the top left-hand corner is cluster 0 and the number 60, which indicates genes. Overall, cluster 0 (), cluster 1 (), cluster 2 (), cluster 3 (), cluster 4 (), cluster 5 (), cluster 6 (), cluster 7 (), and cluster 8 (). The first black diamond represents day 9, followed by days 16, 23, 30, 37, 44, 51, 58, 65, 72, and 79 as the remainder of the sampled days. The red lines on either side of the blue line connecting the black diamonds represent the confidence interval.