Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster

Table 4

Distribution of genes differentially regulated at day 79 from PANTHER analysis. The last time point sampled in the analysis was day 79, which represents the oldest living females. The numbers in the table are the number of genes for each SOM that are either upregulated, downregulated, or unaffected at day 79 compared to the day 2 control time point. The numbers in parentheses are the % of genes that are either upregulated, downregulated, or unaffected at day 79 compared to the day 2 control time point. The genes found in SOM clusters 0 and 8 are 100% affected at day 79.

SOM class	Total number of genes	Upregulated	Downregulated	Unaffected
0	60	0 (0)	60 (100)	0 (0)
1	120	0 (0)	113 (94.2)	7 (5.8)
2	244	1 (0.41)	67 (27.5)	176 (72.1)
3	267	0 (0)	213 (79.8)	54 (20.2)
4	234	11 (4.7)	0 (0)	223 (95.3)
5	127	115 (90.6)	0 (0)	12 (9.4)
6	233	1 (0.43)	54 (23.2)	178 (76.4)
7	254	90 (35.4)	0 (0)	164 (64.6)
8	42	42 (100)	0 (0)	0 (0)
Total	1581	260 (16.4)	507 (32.1)	814 (51.5)