Altered Body Weight Regulation in CK1ε Null and tau Mutant Mice on Regular Chow and High Fat Diets

Figure 1

Altered body weight and fat mass in CK1ε mutant mice. (a) Growth curves of mice on RC diet. (b) Growth curves of mice on HF diet. (c) Total body weight gain after six weeks of either RC or HF diet. Body weight gain was calculated by subtracting the baseline weight at the beginning of the diet experiment from weight at the end of the diet experiment. (d) The gonadal fat pads from mice fed either RC or HF diet were weighed at the end of study. CK1ε^+/+ (black), CK1 (blue), and CK1 (red) mice were on a 24 hr LD cycle; CK1 mice kept on a 20 hr LD cycle are represented in yellow. Mean values are presented for each group, with error bars representing SEM. Asterisks indicate significant differences between groups ().

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