Research Article
Serotonin-Related Gene Polymorphisms and Asymptomatic Neurocognitive Impairment in HIV-Infected Alcohol Abusers
Table 3
TPH2 and GALM associations with cognitive impairment stratified by sex and race/ethnicity (ORs and 95% CIs).
| | Gene | Variant | Domain | OR allele (95% CI) | value | OR sex (95% CI) | value | OR race (95% CI) | value | OR race × sex (95% CI) | value |
| | TPH2 | rs4570625 | Executive function | 2.5 (1.1 to 4.9) | | 4.0 (1.6 to 10.5) | = 0.007 | 3.3 (1.4 to 7.6) | | 4.8 (1.5 to 14.8) | | | GALM | rs6741892 | Memory | 1.9 (1.2 to 3.1) | | 2.3 (1.2 to 4.2) | = 0.009 | 1.9 (1.1 to 3.6) | | 2.4 (1.2 to 4.9) | |
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OR stratified by sex, OR stratified by race, OR stratified by sex and race.
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