Leveraging Comparative Genomics to Identify and Functionally Characterize Genes Associated with Sperm Phenotypes in Python bivittatus (Burmese Python)

Table 3

Identification of KEGG pathways enriched for genes within Python bivittatus genes associated with sperm phenotypes.

Pathway-ID	Pathway name	Count	Genes	Enrichment	value
hsa05200	Pathways in cancer	10	LAMA2, FOS, AR, PDGFA, RXRB, BAX, NOS2, KIT, FAS, CCNA1	3.45	1.64E − 03
hsa04115	p53 signaling pathway	4	BAX, APAF1, FAS, ATM	6.65	2.05E − 02
hsa05222	Small cell lung cancer	4	LAMA2, RXRB, APAF1, NOS2	5.38	3.54E − 02
hsa04210	Apoptosis	4	BAX, APAF1, FAS, ATM	5.20	3.87E − 02
hsa04020	Calcium signaling pathway	5	ATP2B4, CAMK4, PLCD4, NOS2, BDKRB2	3.21	6.44E − 02
hsa04060	Cytokine-cytokine interaction	6	LEP, AMHR2, AMH, PDGFA, KIT, FAS	2.59	7.38E − 02

Identification of KEGG pathways enriched for genes within Python bivittatus genes associated with sperm phenotypes. KEGG pathways were identified using the bioinformatics resource DAVID. The KEGG pathway identifier and pathway name are provided along with the number of genes identified in the pathway, the gene symbol for each identified gene, the fold enrichment, and the associated value.