Molecular Characterization of a Novel Germline<i> VHL</i> Mutation by Extensive<i> In Silico</i> Analysis in an Indian Family with Von Hippel-Lindau Disease

<div>(a) Superimposed structure of native and mutant structure of VHL. (b) Close-up view of native amino acid leucine (orange) and mutant amino acid glutamine (blue) in dot. (c) Local environment change visualized for native amino acid [leucine] in dot model. (d) Local environment change visualized for mutant amino acid [glutamine] in dot model. These figures were drawn using Chimera.</div>

Genetics Research International

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Figure 4

Figure 4: Molecular Characterization of a Novel Germline<i> VHL</i> Mutation by Extensive<i> In Silico</i> Analysis in an Indian Family with Von Hippel-Lindau Disease 

Figure 4 | Molecular Characterization of a Novel Germline VHL Mutation by Extensive In Silico Analysis in an Indian Family with Von Hippel-Lindau Disease 