Genetic Variants in CSMD1 Gene Are Associated with Cognitive Performance in Normal Elderly Population

Table 3

Odds ratio values for lower MoCA score for alleles, genotypes, and haplotypes of CSMD1 genetic variants in comparison of lower (Q1) and upper (Q4) quartiles of MoCA score distribution.

Allele, genotype, haplotype	OR	95% CI	Chi-square
rs10503253
А	1,04	0.74–1,46	0.06	0,799
C	0.96	0.68–1.35	0.06	0.799
АA	0.95	0.42–2.16	0.01	0.905
CА	1.13	0.73–1.76	0.34	0.562
CC	0.90	0.58–1.37	0.29	0.592
rs2616984
A	1,49	1,07–2,07	6,01	0,014
G	0.67	0.48–0.94	6.01	0.0142
AA	1.70	1.11–2.61	6.64	0.0099
AG	0.65	0.42–1.00	4.25	0.039
GG	0.70	0.32–1.51	0.96	0.326
rs10503253/rs2616984 haplotypes
CA	1,27	0,94–1,70	2,63	0,105
CG	0,67	0,47–0,97	4,97	0,026
AA	1,15	0,79–1,69	0,59	0,443
AG	0,81	0,44–1,47	0,55	0,457

Significant values are in bold.