Genetics Research International

Molecular Genetics and Cytogenetics in Cancer


Publishing date
01 Nov 2011
Status
Published
Submission deadline
01 May 2011

1Centro de Investigación del Cáncer, Universidad de Salamanca, 37007 Salamanca, Spain

2Hospital Universitario de Salamanca, Paseo de San Vicente 58-182, 37007 Salamanca, Spain

3Laboratory of Molecular Biology, Bone Marrow Transplantation Center (CEMO), National Cancer Institute, Rio de Janeiro, Brazil


Molecular Genetics and Cytogenetics in Cancer

Description

For many years, a growing body of information has established cancer as a genetic-associated disease driven by the accumulation of multiple abnormalities. The identification of specific genetic abnormalities responsible for tumor diversity and heterogeneity is of the most importance to understand the mechanisms responsible for tumorigenesis, to predict genetically derived drug resistance and accordingly, to design successful patient-specific targeted therapies.

In this special issue, we invite investigators to contribute with original research as well as review articles focusing on new advances in the field of cytogenetics for the differential diagnosis, prognosis, and disease monitoring as well as for targeted therapies and response predictors, both in solid and hematological malignancies. We are particularly interested in articles describing the intratumoral patterns of clonal evolution and tumor progression pathways specific to each tumor type and their relationship with tumor histopathology and behavior. Potential topics include, but are not limited to:

  • Identification of recurrent genetic abnormalities in different tumor types
  • Hypothetic models of clonal evolution based on genetic abnormalities at intratumoral level
  • Clinical utility of molecular cytogenetics for disease classifications and risk groups stratification
  • Previously unreported applications of molecular cytogenetic techniques
  • Technical strategies for detection of chromosomal abnormalities
  • Development of new techniques or significant enhancements to established techniques

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/gri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 835053
  • - Editorial

Molecular Genetics and Cytogenetics in Cancer

José María Sayagués | Sergio Roa | ... | Ilana Zalcberg Renault
  • Special Issue
  • - Volume 2011
  • - Article ID 219189
  • - Review Article

Molecular Aspects of Breast Cancer Metastasis to the Brain

Jodi M. Saunus | Majid Momeny | ... | Leonard Da Silva
  • Special Issue
  • - Volume 2011
  • - Article ID 980150
  • - Research Article

Integrated Genomic Analysis of Sézary Syndrome

Xin Mao | Tracy Chaplin | Bryan D. Young
  • Special Issue
  • - Volume 2011
  • - Article ID 643628
  • - Review Article

The Role of Dicentric Chromosome Formation and Secondary Centromere Deletion in the Evolution of Myeloid Malignancy

Ruth N. MacKinnon | Lynda J. Campbell
  • Special Issue
  • - Volume 2011
  • - Article ID 798089
  • - Review Article

Genetic Markers Used for Risk Stratification in Multiple Myeloma

Priscilla Segges | Esteban Braggio
  • Special Issue
  • - Volume 2011
  • - Article ID 275802
  • - Review Article

Molecular Alterations in Sporadic Primary Hyperparathyroidism

Maria Inês Alvelos | Maria Mendes | Paula Soares
  • Special Issue
  • - Volume 2011
  • - Article ID 497148
  • - Review Article

Cytogenetics and Molecular Genetics of Myxoid Soft-Tissue Sarcomas

Jun Nishio | Hiroshi Iwasaki | ... | Masatoshi Naito

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