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Progress on Molecular Genetics of Aging and Antiaging

Call for Papers

A higher percentage of the elderly in the population increases the prevalence of chronic diseases and disability. Aging causes organs degradation, dysfunction, and diseases, even leading to organs failure or death. However, to date, the major medical studies are based on the normal adult models instead of the elder ones. Although DNA methylation has an important role in regulation of transcriptional programs and systematically varies as a function of age, the molecular-genetic contributions of age-related changes are largely unknown. The predicament of lack of biomedical investigation for aging limits the understanding of age-related diseases and thus retards the effective interventions for these diseases.

The purpose of this special issue is to publish high-quality research articles as well as reviews that seek to address recent progress on molecular genetics of aging and age-related diseases to insight view on genetic contributions of age-related changes. The fundamental issues in the biology of aging on genetics with further clinic significance are acceptable as well.

Potential topics include but are not limited to the following:

  • Animal models for aging research and its applications
  • The genetic and epigenetic diversity among individuals and between populations for aging
  • New molecular-genetic biomarkers for the assessment of aging and age-related diseases
  • Novel antiaging interventions in preclinical and clinical research based on genetic understanding on aging
  • Other research on aging and clinical epidemiological and psychological aspects of later life, especially based on genetics approach

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 8 December 2017
Publication DateApril 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Lead Guest Editor

Guest Editors

  • Huijing Wang, Shanghai University of Medicine & Health Sciences, Shanghai, China
  • Niels Eijkelkamp, University Medical Center Utrecht, Utrecht, Netherlands
  • Yun Liu, Fudan University, Shanghai, China
  • Wei Liu, University of Pennsylvania, Philadelphia, USA