Clinical Study

Rectal Visceral Sensitivity in Women with Irritable Bowel Syndrome without Psychiatric Comorbidity Compared with Healthy Volunteers

Table 4

Rectal baseline volume (tone) and volume at the distension of 8 mmHg and 24 mmHg in 38 IBS patients without comorbid psychiatric disorders (subdivided into IBS patients with diarrhoea and alternating stool habits), in 11 IBS patients with phobic anxiety and in 9 healthy volunteers. Values are mean ± SD; pressure is reported in mmHg, volume in Ml; the baseline volume was only registered in 34 IBS patients without psychiatric comorbidity and 9 IBS patients with comorbid phobic anxiety. The volume at 8 mmHg distension was only registered in 10 IBS patients without comorbid phobic anxiety. The volume at 24 mmHg distension was only registered in 34 IBS patients without psychiatric comorbidity, 10 IBS patients with comorbid phobic anxiety, and 8 healthy volunteers.

IBS patients without psychiatric disordersIBS patients with phobic anxietyHealthy volunteers
AllDiarrhoea predominantAlternating stool habits

Baseline
Pressure7.5 ± 1.37.8 ± 1.77.5 ± 0.97.4 ± 1.37.2 ± 1.2
Volume79 ± 4 60 ± 3 91 ± 5650 ± 2 127 ± 59
8 mmHg distension
Volume46 ± 4043 ± 3848 ± 4443 ± 3266 ± 37
24 mmHg distension
Volume171 ± 59 179 ± 60171 ± 44216 ± 58

from healthy volunteers from healthy volunteers.