Gastroenterology Research and Practice / 2009 / Article / Tab 3

Clinical Study

Short Bowel Patients Treated for Two Years with Glucagon-Like Peptide 2: Effects on Intestinal Morphology and Absorption, Renal Function, Bone and Body Composition, and Muscle Function

Table 3

Diet, feces, absorption (diet-feces), and urine excretion of wet weight, sodium, potassium, calcium, and magnesium.

(mean SD, )1st year2nd year
BaselineWeek 13Week 26Week 52WashoutWeek 13Week 26Week 52 -value*

TreatmentNoneGLP-2GLP-2GLP-2NoneGLP-2GLP-2 + Cholyl-sarcosine#GLP-2

Wet weight (g/d)
Diet
Feces .001
Abs. absorption
Rel. absorption .001
Urine
Sodium (mmol/d)
Diet
Feces
Abs. absorption
Rel. absorption
Urine
Potassium (mmol/d)
Diet
Feces .001
Abs. absorption
Rel. absorption .001
Urine .001
Calcium (mmol/d)
Diet .001
Feces .001
Abs. absorption
Rel. absorption
Urine
Magnesium (mmol/d)
Diet
Feces
Abs. absorption
Rel. absorption
Urine

*Friedman repeated measures analysis of variance on ranks in patients completing the study. For comparisons of admission periods to the baseline period, the Dunnett method was used as the post hoc test. . Cholylsarcosine was given two days prior to the admission and during the 72-hour balance studies.

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