TY - JOUR
A2 - Kahaleh, Michel
AU - Kawamura, Yutaka J.
AU - Tokumitsu, Aika
AU - Sasaki, Junichi
AU - Tsujinaka, Shingo
AU - Maeda, Takafumi
AU - Mizogami, Ken
AU - Konishi, Fumio
PY - 2009
DA - 2009/08/24
TI - Colorectal Carcinoma with Extremely Low CA19-9
SP - 780263
VL - 2009
AB - Aim. The aim of this study is to determine the significance of postoperative sequential measurements of serum CA19-9 in patients with extremely low serum level. Patients and Methods. Serum level of CA19-9 of 1096 patients who underwent surgery was measured preoperatively and every three months after surgery for 5 years. Patients with CA19-9 level of less than 2 U/mL at the time of diagnosis were defined as Extremely Low CA19-9 (ELCA). Results. One hundred and seven patients (9.8%) were ELCA. Of these, 86 underwent surgery with curative intent. Serum levels of CA19-9 in patients who did not undergo curative resection (N=12) and who developed recurrence (N=10) were less than 2.0 U/mL in all occasions during followup. In all patients without recurrence, serum level of CA19-9 also remained less than 2.0 U/mL. Conclusion. In patients with extremely low CA19-9, who consist of 9.8% of colorectal carcinoma cases, postoperative sequential measurement of serum level of CA19-9 contributed neither to assessment of curability of surgical resection nor to detection of recurrence.
SN - 1687-6121
UR - https://doi.org/10.1155/2009/780263
DO - 10.1155/2009/780263
JF - Gastroenterology Research and Practice
PB - Hindawi Publishing Corporation
KW -
ER -