Table of Contents Author Guidelines Submit a Manuscript
Gastroenterology Research and Practice
Volume 2010 (2010), Article ID 537263, 8 pages
http://dx.doi.org/10.1155/2010/537263
Review Article

Toll-Like Receptors in Hepatic Ischemia/Reperfusion and Transplantation

Department of Surgery, University of Pittsburgh School of Medicine, 200 Lothrop St., Pittsburgh, PA 15213, USA

Received 28 April 2010; Accepted 8 July 2010

Academic Editor: Ekihiro Seki

Copyright © 2010 John Evankovich et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [19 citations]

The following is the list of published articles that have cited the current article.

  • Hai Huang, John Evankovich, Wei Yan, Gary Nace, Lemeng Zhang, Mark Ross, Xinghua Liao, Timothy Billiar, Jun Xu, Charles T. Esmon, and Allan Tsung, “Endogenous Histones Function as Alarmins in Sterile Inflammatory Liver Injury Through Toll-like Receptor 9 in Mice,” Hepatology, vol. 54, no. 3, pp. 999–1008, 2011. View at Publisher · View at Google Scholar
  • Justin D. Ellett, Carl Atkinson, Zachary P. Evans, Zainab Amani, Edward Balish, Michael G. Schmidt, Rick G. Schnellmann, and Kenneth D. Chavin, “Toll-Like Receptor 4 Knockout Mice Are Protected From Endothelial Overactivation in the Absence of Kupffer Cells After Total Hepatic Ischemia/Reperfusion,” Liver Transplantation, vol. 17, no. 9, pp. 1089–1098, 2011. View at Publisher · View at Google Scholar
  • R. Thuillier, D. Dutheil, M. T. N. Trieu, V. Mallet, G. Allain, M. Rousselot, M. Denizot, J.-M. Goujon, F. Zal, and T. Hauet, “Supplementation With a New Therapeutic Oxygen Carrier Reduces Chronic Fibrosis and Organ Dysfunction in Kidney Static Preservation,” American Journal of Transplantation, vol. 11, no. 9, pp. 1845–1860, 2011. View at Publisher · View at Google Scholar
  • John Evankovich, Ruilin Zhang, Jon S. Cardinal, Lemeng Zhang, Junda Chen, Hai Huang, Donna Beer-Stolz, Timothy R. Billiar, Matthew R. Rosengart, and Allan Tsung, “Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy,” American Journal Of Physiology-Gastrointestinal And Liver Physiology, vol. 303, no. 2, pp. G189–G198, 2012. View at Publisher · View at Google Scholar
  • Madhu V. Singh, Paari D. Swaminathan, Elizabeth D. Luczak, W. Kutschke, Robert M. Weiss, and Mark E. Anderson, “MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction,” Journal of Molecular and Cellular Cardiology, vol. 52, no. 5, pp. 1135–1144, 2012. View at Publisher · View at Google Scholar
  • H. Krichen, Y. Gorgi, T. Dhaouadi, Y. Mecheri, I. Sfar, R. Bardi, M.M. Bacha, E. Abderrahim, S. Jendoubi-Ayed, K. Ayed, and T. Ben Abdallah, “Toll-Like Receptor 4 and CD14 Gene Polymorphisms in Tunisian Kidney Transplantation,” Transplantation Proceedings, vol. 45, no. 10, pp. 3472–3477, 2013. View at Publisher · View at Google Scholar
  • Sodam Kim, Sun Young Kim, John P. Pribis, Michael Lotze, Kevin P. Mollen, Richard Shapiro, Patricia Loughran, Melanie J. Scott, and Timothy R. Billiar, “Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14,” Molecular Medicine, vol. 19, pp. 88–98, 2013. View at Publisher · View at Google Scholar
  • Timothy R. Billiar, Charles T. Esmon, John Evankovich, Wei Yan, Patricia Loughran, Donna Beer-Stolz, Gary W. Nace, Qing Ding, Hui-Wei Chen, Hai Huang, Allan Tsung, and Brian R. Rosborough, “Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury,” Journal Of Immunology, vol. 191, no. 5, pp. 2665–2679, 2013. View at Publisher · View at Google Scholar
  • Miao Shen, Jie Lu, Weiqi Dai, Fan Wang, Ling Xu, Kan Chen, Lei He, Ping Cheng, Yan Zhang, Chengfen Wang, Dong Wu, Jing Yang, Rong Zhu, Huawei Zhang, Yinqun Zhou, and Chuanyong Guo, “Ethyl Pyruvate Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Intrinsic Pathway of Apoptosis and Autophagy,” Mediators of Inflammation, vol. 2013, pp. 1–12, 2013. View at Publisher · View at Google Scholar
  • Kerry-Ann McDonald, Hai Huang, Samer Tohme, Patricia Loughran, Kimberly Ferrero, Timothy Billiar, and Allan Tsung, “Toll-like Receptor 4 (TLR4) Antagonist Eritoran Tetrasodium Attenuates Liver Ischemia and Reperfusion Injury through Inhibition of High-Mobility Group,” Molecular Medicine, vol. 20, pp. 639–648, 2014. View at Publisher · View at Google Scholar
  • Mona F Mahmoud, Samar Gamal, and Hassan M. El-Fayoumi, “Limonin attenuates hepatocellular injury following liver ischemia and reperfusion in rats via toll-like receptor dependent pathway,” European Journal of Pharmacology, 2014. View at Publisher · View at Google Scholar
  • Selcuk Kilinc, Sedat Tan, Efsun Hatice Kolatan, Dane Ruscuklu, Esra Satici, Mehmet Kemiksiz, Lutfi Dalkilic, Umut Eren Erdogdu, and Cezmi Karaca, “The effects of preoperative immunosuppressive therapy on ischemia and reperfusion (I/R) injury in healthy rats,” International Urology and Nephrology, vol. 46, no. 2, pp. 389–393, 2014. View at Publisher · View at Google Scholar
  • Xavier Wittebole, Pierre-Francois Laterre, and Steven M. Opal, “Targeting Toll-Like Receptors 4 Intracellular Domain to Prevent Ischemic Liver Disease: An Innovative Approach or Just a Futuristic Dream?,” Critical Care Medicine, vol. 42, no. 2, pp. 487–488, 2014. View at Publisher · View at Google Scholar
  • Ying Yang, Shuping Li, Qiao Yang, Yu Shi, Min Zheng, Yanning Liu, Feng Chen, Guangzhong Song, Hangdi Xu, Tianhong Wan, Jiliang He, and Zhi Chen, “Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells,” Cellular Physiology and Biochemistry, vol. 33, no. 5, pp. 1283–1292, 2014. View at Publisher · View at Google Scholar
  • Qianni Hu, Caroline Ruth Wood, Sanem Cimen, Ananda Baskaran Venkatachalam, and Ian Patrick Joseph Alwayn, “Mitochondrial Damage-Associated Molecular Patterns (MTDs) Are Released during Hepatic Ischemia Reperfusion and Induce Inflammatory Responses,” Plos One, vol. 10, no. 10, 2015. View at Publisher · View at Google Scholar
  • Hamza Obaid Yazdani, Hai Huang, Ahmed B. Al-Khafaji, Samer Tohme, David Miller, and Allan Tsung, “Superoxide induces neutrophil extracellular trap formation in a TLR-4 and NOX-dependent mechanism,” Molecular Medicine, vol. 22, pp. 621–631, 2016. View at Publisher · View at Google Scholar
  • Safak Kiziltas, “Toll-like receptors in pathophysiology of liver diseases,” World Journal of Hepatology, vol. 8, no. 32, pp. 1354–1369, 2016. View at Publisher · View at Google Scholar
  • Thiago Henrique Caldeira de Oliveira, Pedro Elias Marques, Paul Proost, and Mauro Martins M Teixeira, “Neutrophils: a cornerstone of liver ischemia and reperfusion injury,” Laboratory Investigation, 2017. View at Publisher · View at Google Scholar
  • Eunyoung Chun, Ki-Young Lee, Yoon Min, Sae M. Wi, and Dongwoo Shin, “Peroxiredoxin-6 negatively regulates bactericidal activity and NF-κB activity by interrupting TRAF6-ECSIT complex,” Frontiers in Cellular and Infection Microbiology, vol. 7, 2017. View at Publisher · View at Google Scholar