Analysis of KRAS Mutations of Exon 2 Codons 12 and 13 by SNaPshot Analysis in Comparison to Common DNA Sequencing
Figure 1
The electropherograms of the SNaPshot analysis (a) and the DNA sequencing (b) of the same tumor tissue sample. The mutation of codon 12 position 2 guanine to adenine transition is definitely visible in the SNaPshot analysis. In the sequencing analysis, the adenine-peak is hardly distinguishable from the background.