The Regenerating Gene I Is Overexpressed in Atrophic Gastritis Rats with Hypergastrinemia
Figure 1
Pathological finding in rats with atrophic gastritis. (a) Gloss appearance of gastric mucosa. Flat with pale appearance and thin mucin on the gastric mucosa in atrophic gastritis group rats (right diagram) when compared with normal rats (left diagram). (b) H&E (×100) staining of gastric gland. Irregular arrangement and cystic dilation of gastric glands in atrophic gastritis (right diagram). (c) H&E (×200) staining showed that neutrophils and lymphocytes infiltrated into the gastric glands in rats with atrophic gastritis (right diagram). (d) The mean number of infiltrated inflammatory cells was calculated in each of 10 microscopic fields of gastric antrum glands. The mean inflammation score (mean ± s.d) was 1.95 ± 0.55 and 1.3 ± 0.34, respectively, in atrophic gastritis and normal rats. (e) The number of gastric glands in each of 1 mm area (mean ± SD) was randomly analyzed in 5 microscopic fields, which was 39.8 ± 4.59 and 44.2 ± 2.57, respectively, in atrophic gastritis and normal rats. Normal group: normal rats; Model group: atrophic gastritis rats. *.
