Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review

Table 2

Risk of mortality and complications due to hyperglycemia in patients receiving PN.

Study	Cheung (2005)	Lin (2007)	Sarkisian (2009)	Pasquel (2009)
Hyperglycemia(mmol/L)	>9.1*	>10**	>10***	>10****
Mortality OR(95%CI)	10.90(2.0−60.5)^X	5.0(2.4−10.6)^X	7.22(1.08−48.3)^X	2.80(1.20−6.80)^X
Any Infection OR(95%CI)	3.9(1.2−12.0)^X	3.1(1.5−6.5)^X	0.9(0.3−2.5)	NA
Cardiac OR(95%CI)	6.2(0.7−57.8)	1.6(0.3-7.2)	1.3(0.1−12.5)	NA
Acute Renal Failure OR(95%CI)	10.9(1.2−98.1)^X	3.0(1.2−7.7)^X	1.9(0.4−8.6)	2.2(1.0−4.8)
Septicemia OR(95%CI)	2.5(0.7−9.3)	NA	NA	NA
Any Complication OR(95%CI)	4.3(1.4−13.1)^X	5.5(2.5−12.4)^X	NA	NA

All study results are adjusted for age and sex.
X Significant at 𝑃<.05.
*ORs are expressed using blood glucose <6.9 mmol/L as a reference category.
**ORs are expressed using blood glucose <6.3 mmol/L as a reference category.
***ORs are expressed using blood glucose <10 mmol/L as a reference category.
****ORs are expressed using blood glucose <6.7 mmol/L as a reference category as measured within 24 hours of PN initiation.