Clinical Study

The Histological and Immunohistochemical Aspects of Bile Reflux in Patients with Gastroesophageal Reflux Disease

Table 2

Endoscopic and histologic data in GERD patients and healthy controls.

GERD patients
( )
Healthy controls
( )

Esophagus

Endoscopy, n (%)
  Esophagitis grade
 020 (37.7)15 (100)
 A15 (28.3)0
 B13 (24.5)0
 C3 (5.6)0
 D00
  Barrett’s3 (5.6)0
  Hernia18 (33.9)4 (26.6)
  Presence of bile4 (7.5)0
Histology, n (%)
  Esophagitis45* (84.9)8 (53.3)
  Barrett’s3(5.6)0
  Dysplasia00

Stomach

Endoscopy, n (%)
  Gastritis
  No11 (20.7)10 (66.6)
  Mild30* (56.6)5 (33.3)
  Erosive12* (22.6)0
  Presence of bile 27* (50.9)3 (20)
Histology, n (%)
  Gastritis 50 (94.3)10 (66.6)
  Atrophy 17* (32)1 (6.6)
  H. pylori (yes) 16 (30.2)3 (20)
  Cardiac metaplasia 5 (9.4)1 (6.6)
  Antrum metaplasia 12* (22.6)0
  Dysplasia 00

Statistically significant differences are marked with asterisk (*).