Clinical Study
The Histological and Immunohistochemical Aspects of Bile
Reflux in Patients with Gastroesophageal Reflux
Disease
Table 2
Endoscopic and histologic data in GERD patients and healthy controls.
| | GERD patients () | Healthy controls () |
| | Esophagus | |
| Endoscopy, n (%) | | | Esophagitis grade | | | 0 | 20 (37.7) | 15 (100) | A | 15 (28.3) | 0 | B | 13 (24.5) | 0 | C | 3 (5.6) | 0 | D | 0 | 0 | Barrett’s | 3 (5.6) | 0 | Hernia | 18 (33.9) | 4 (26.6) | Presence of bile | 4 (7.5) | 0 | Histology, n (%) | | | Esophagitis | 45* (84.9) | 8 (53.3) | Barrett’s | 3(5.6) | 0 | Dysplasia | 0 | 0 |
| | Stomach | |
| Endoscopy, n (%) | | | Gastritis | | | No | 11 (20.7) | 10 (66.6) | Mild | 30* (56.6) | 5 (33.3) | Erosive | 12* (22.6) | 0 | Presence of bile | 27* (50.9) | 3 (20) | Histology, n (%) | | | Gastritis | 50 (94.3) | 10 (66.6) | Atrophy | 17* (32) | 1 (6.6) | H. pylori (yes) | 16 (30.2) | 3 (20) | Cardiac metaplasia | 5 (9.4) | 1 (6.6) | Antrum metaplasia | 12* (22.6) | 0 | Dysplasia | 0 | 0 |
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Statistically significant differences are marked with asterisk (*).
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