Colorectal Oncogenesis and Inflammation in a Rat Model Based on Chronic Inflammation due to Cycling DSS Treatments

Table 5

Short-chain fatty acids. Distribution between acetic, propionic, and butyric acid (%) in the gut content of rats in different treatment groups^1,2.

	Normal		DSS		AOM
	Mean	SEM	Mean	SEM	Mean	SEM
Caecum^3
Acetic	55.1^a	2.6	66.0^b	1.4	62.1^a,b	2.8
Propionic	14.4	0.6	16.9	1.1	14.7	0.8
Butyric	30.5^a	2.4	17.1^b	1.1	23.2^a,b	2.7
Proximal^3
Acetic	62.2^a	1.8	69.5^b	1.2	65.2^a,b	1.5
Propionic	17.8	0.9	16.1	1.0	15.5	0.8
Butyric	20.0^a	1.1	14.4^b	1.4	19.4^a	1.6
Distal^4
Acetic	57.6^a	1.5	66.4^b	1.5	63.7^b	1.4
Propionic	17.2	1.7	18.4	1.5	17.2	1.3
Butyric	25.2^a	2.2	15.3^b	1.6	19.1^a,b	1.5

¹Mean values with their standard errors of mean for 8 rats per group.
²Mean values with unlike superscript letters in the same line were significantly different (𝑃<0.05).
³AOM, 𝑛=7.
⁴AOM, 𝑛=5.