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| Factor | Study | Result |
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Disease-related factors | Disease activity | Vidal et al. [74] | Disease activity was one of strongest predictors of QOL impairments. |
Albersnagel and Dijkstra [72] | Disease activity adversely affects QOL of the patients. |
Haapamaki [71] | Disease activity was the most factors related to QOL impairment. |
Graff et al. [73] | Patients with active disease had poorer QOL scores, but participants with either active or inactive disease had suboptimal general QOL. |
Disease severity | Guthrie et al. [58] | Disease severity was one of factors contributed to impaired QOL. |
Disease type | Mikocka-Walus et al. [40] | CD patients tended to have poorer physical QOL than UC patients. |
Casellas et al. [70] | Disease type did not predict QOL scores. |
Guthrie et al. [58] | After controlling disease severity, there were no significant differences between CD and UC in QOL scores. |
Graff et al. [73] | Disease type was not contributor to QOL. |
History of surgery | Haapamaki [71] | Lower QOL scores were seen in those patients with a history of surgery. |
Disease chronicity | Haapamaki [71] | Lower QOL scores were seen in newly diagnosed patients. |
Casellas et al. [70] | Longer disease duration and lower recurrence/year index predicted a better QOL. |
Need for hospitalization | Casellas et al. [70] | Nonnecessity of hospitalization predicted a better QOL. |
|
Demographic factors | Gender | Haapamaki [71] | Female had poorer QOL than men. |
Casellas et al. [70] | Female gender predicted a better QOL. |
Age | Haapamaki [71] | Older age patients had poorer QOL. |
Educational level | Casellas et al. [70] | Higher level of education predicted a better QOL. |
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Psychological factors | Personality | Vidal et al. [74] | Personality traits did not play a significant role in QOL. |
Moreno-Jiménez et al. [44] | Neuroticism and greater difficulty in describing feelings to others were related to poorer QOL. |
Psychological distress | Vidal et al. [74] | Psychological distress was one of strongest predictors of QOL impairments. |
Guthrie et al. [58] | Psychological symptoms were one of factors contributed to impaired QOL. |
Social support | Moradkhani [76] | Activity in online support groups was not related to QOL. |
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