Review Article

Fecal Molecular Markers for Colorectal Cancer Screening

Table 2

Studies of SFRP2 genetic alterations in fecal samples.

Authors and referencesTechniqueSpecimenSpecimen =Control =SensitivitySpecificity

Tang et al. [63]MS-PCRCRC
Adenoma
169
63
3084%
46%
54%
Wang and Tang [64]Fluorescence-based RT-PCRCRC
Adenoma
69
34
3087.0%
61.8%
93.3%
Oberwalder et al. [26]MethyLight analysisAdenoma13646%100%
Huang et al. [62]MS-PCRCRC
Adenoma
52
21
2494.2%
52.4%
95.8%
Müller et al. [65]MethyLight analysisCRC131377%77%