Gastroenterology Research and Practice

Research Article

The Impact of Host Metabolic Factors on Treatment Outcome in Chronic Hepatitis C

Table 1

Demographic, virological, and histological data according to genotype.
Genotype 1
𝑛 = 1 6 4 		Genotype 2
𝑛 = 2 3 		Genotype 3
𝑛 = 1 1 3 		Genotype 4
𝑛 = 4 6 		𝑃 values*
Gender (males%)87 (53.0)12 (52.2)66 (58.4)24 (53.3) 0.826
Age ≥ 40 years ( 𝑛 %)110 (67.5)19 (82.6)41 (36.9)30 (68.2)<0.001
IVDU ( 𝑛 %)40 (24.4)3 (13.0)59 (52.7)6 (13.3)<0.001
Alcohol abuse ( 𝑛 %)15 (9.3)2 (8.7)17 (15.7)6 (14.0) 0.392
BMI (kg/m2) 2 3 . 6 ± 4 . 8 2 6 . 4 ± 3 . 9 2 3 . 2 ± 3 . 4 2 3 . 5 ± 4 . 1 0.144
Overweight ( 𝑛 %)15 (32.6)7 (70.0)18 (32.1)8 (40.0) 0.126
High viral load ( 𝑛 %)23 (33.3)3 (37.5)32 (55.2)9 (42.9) 0.101
Hepatic steatosis ( 𝑛 %)46 (28.2)8 (34.8)37 (32.7)16 (35.6) 0.721
Severe inflammation ( 𝑛 %)10 (6.5)0 (0)3 (2.9)2 (4.7) 0.406
Advanced fibrosis ( 𝑛 %)23 (14.1)4 (17.4)17 (15.3)11 (24.4) 0.411
Cirrhosis ( 𝑛 %)7 (4.3)1 (4.3)8 (7.2)5 (11.1) 0.356
*Comparison between genotypes with 𝜒 2 (nonparametrical) or one-way ANOVA (parametrical variables).