Review Article

Confocal Endomicroscopy of Colorectal Polyps

Table 1

Colorectal pathology prediction using confocal pattern classification.

GradeVessel architectureCrypt architecture

NormalHexagonal, honeycomb appearanceRegular luminal openings, homogenous layer of epithelial cells
RegenerationHexagonal, honeycomb appearance with no or mild increase in the number of capillariesStar-shaped luminal crypt openings or focal aggregation of regular-shaped crypts with a regular or reduced amount of goblet cells
NeoplasiaDilated and distorted vessels; irregular architecture with little or no orientation to adjunct tissueRidged-lined irregular epithelial layer with loss of crypts and goblet cells; irregular cell architecture with little or no mucin