Pantoprazole before Endoscopy in Patients with Gastroduodenal Ulcer Bleeding: Does the duration of Infusion and Ulcer Location Influence the Effects?

Table 1

Characteristics of 333 gastroduodenal ulcer bleeding patients included in the retrospective analysis.

Characteristic	Pantoprazole (𝑛=240)	Saline (𝑛=93)	P value
Age—year	63.4 ± 15.2	66.0 ± 13.4	0.12
Male sex—number (%)	175 (72.9%)	59 (63.4%)	0.08
Hemoglobin—g/dL	95.3 ± 30.1	96.8 ± 30.4	0.68
Shock symptoms—number of patient (%)	22 (9.2%)	3 (3.2%)	0.06
Coexisting illness—number of patients (%)
Cirrhosis	40 (16.6%)	16 (17.2%)	0.90
Cardiovascular	146 (60.8%)	58 (62.3%)	0.79
Helicobacter pylori infection—number of patients (%)	73 (30.4%)	33 (35.4%)	0.37
Risk factors for bleeding—number of patients (%)
NSAID and/or aspirin	120 (50.0%)	42 (45.2%)	0.42
Anticoagulant	19 (7.9%)	8 (8.6%)	0.83
Previous gastroduodenal ulcer	74 (30.8%)	28 (30.1%)	0.89
Source of bleeding
Duodenal ulcer	128 (53.3%)	47 (50.5%)	0.64
Gastric ulcer	112 (46.7%)	46 (49.5%)	0.64
Symptom at presentation—number of patients (%)
Melena	177 (73.7%)	65 (69.9%)	0.47
Hematemesis	111 (46.2%)	36 (38.7%)	0.21
Both	60 (25.0%)	16 (17.2%)	0.12
Duration of infusion before endoscopy (hours)	6.9 ± 13.2	5.45 ± 12.9	0.29