Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells
Immature DC primed with MF/L. lactis and increasing amounts of recombinant human IL-10 (0, 0.5, 5 and 50 ng/mL). Bar graphs represent the mean inhibition of fluorescence intensity of allogenic Th-cells for the indicated conditions in duplo. The proliferation of allogenic Th-cells cocultured with effector Th-cells derived from MF-matured DC is regarded as 100% (reference condition). Mean percentages with standard error of mean are given; *indicates and **indicates using the -test for comparing percentages with the reference condition (MF).
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