Effect of Non-Anticoagulant N-Desulfated Heparin on Basic Fibroblast Growth Factor Expression, Angiogenesis, and Metastasis of Gastric Carcinoma In Vitro and In Vivo

Table 3

bFGF mRNA expression of gastric cancer SGC-7901 cell in different concentrations (0.1 mg/mL, 1 mg/mL) of N-desulfated heparin groups and control group (ct value, 𝑥±𝑠, 𝑛=3).

	12 hr	24 hr
Control group	25.956±0.505	24.490±0.145^∗
0.1 mg/mL N-desulfated heparin group	30.923±0.612^▵	32.493±0.358^▵
1 mg/mL N-desulfated heparin group	33.826±0.349^▵#	35.446±0.299^▵∗#∗

∗24 hr versus 12 hr, 𝑃<0.05; ▵different concentrations (0.1 mg/mL, 1 mg/mL) of N-desulfated heparin versus control group, 𝑃<0.05; #1 mg/mL N-desulfated heparin group versus 0.1 mg/mL N-desulfated heparin group, 𝑃<0.05.