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Gastroenterology Research and Practice
Volume 2012, Article ID 860879, 5 pages
Review Article

The Endoscopic Management of Pain in Chronic Pancreatitis

Division of Gastroenterology and Hepatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA

Received 3 October 2011; Revised 26 January 2012; Accepted 10 February 2012

Academic Editor: Carlos G. Micames

Copyright © 2012 Adam J. Goodman and Frank G. Gress. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pain resulting from chronic pancreatitis is often debilitating and difficult to manage. Many approaches have been used to treat these patients, including narcotic analgesia, antidepressants, pancreatic enzymes, octreotide, denervation procedures, such as celiac plexus block, and various palliative, decompression, or drainage procedures. Many of these procedures can be performed endoscopically, while others require a more invasive, surgical approach. The effectiveness of these therapies is not only highly variable but also often controversial. This review will discuss the endoscopic options for pain management in patients with chronic pancreatitis and their utility in treating this difficult disease.