Metastatic Pancreatic Cancer: Are We Making Progress in Treatment?

Table 2

Selected metaanalysis of GEM-based combination chemotherapy.

Reference	No. of pts	HR (all)	HR for platinum	HR for 5FU/capecitabine	HR for other agents
Heinemann et al. [12]	4465	0.91*	0.85	0.9	0.99
Sultana et al. [13]	9970	0.91	—	—	—
Vaccaro et al. [14]	2422	0.87	0.94 (cisplatin, 𝑃=0.61)	0.86 (𝑃=0.04)	—
			0.86 (oxaliplatin, 𝑃=0.04)

*ECOG PS 0-1: HR 0.76, 𝑃<0.001; ECOG PS 2: HR 1.08, 𝑃=0.40.
Abbreviations: HR: hazard ratio; 5FU: fluorouracil.