Disposition Kinetics of Taxanes in Peritoneal Dissemination
Figure 5
Values of apparent solid tumor to plasma concentration ratio (Kp, app) of paclitaxel and docetaxel 1 h after an i.p. (40 mg/kg, open column) or i.v. (5 mg/kg, closed column) injection of Taxol and Taxotere into AH130 tumor-bearing rats [15]. Each column with bar represents the mean ± SD of three rats. *Significantly different from docetaxel at .