Review Article

Disposition Kinetics of Taxanes in Peritoneal Dissemination

Figure 5

Values of apparent solid tumor to plasma concentration ratio (Kp, app) of paclitaxel and docetaxel 1 h after an i.p. (40 mg/kg, open column) or i.v. (5 mg/kg, closed column) injection of Taxol and Taxotere into AH130 tumor-bearing rats [15]. Each column with bar represents the mean ± SD of three rats. *Significantly different from docetaxel at .
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