Regulation Effect of Zinc Fingers and Homeoboxes 2 on Alpha-Fetoprotein in Human Hepatocellular Carcinoma

Table 4

Relationship between AFP mRNA expression and clinicopathological parameters in HCC tissues.

Parameter	+ (%)	AFP mRNA; 𝑃 value	OR (95% CI)
Total	38 (60.3)
AFP (μg/L)
<20	2 (15.4)	.001	14.14 (2.78–72.05)
>20	36 (72)
Tumor size (cm)
≤5	9 (50)	.29	1.81 (.60–5.49)
>5	29 (64.4)
Background liver
Without cirrhosis	22 (71)	.09	.41 (.15–1.16)
With cirrhosis	16 (50)
Grade
I-II	29 (67.4)	.09	.40 (.13–1.17)
III-IV	9 (45)
Metastasis
Without	21 (60)	.95	1.03 (.37–2.85)
With	17 (60.7)

AFP: alpha-fetoprotein, CI: confidence interval, HCC: hepatocellular carcinoma, and OR: odds ratio.