Lung and Intestine: A Specific Link in an Ulcerative Colitis Rat Model
Schematic representation of study design. On the day 1, day 15, and day 22, the antigen emulsion was immunized in the paws and groin. On day 29, TNBS-ethanol was instilled into the colon. Clinical observation was performed after 24 hours of TNBS-ethanol enema for 4 consecutive weeks. Rats were weighed every weekend. On the end of 24-hour or 4-week administration, rats were sacrificed, respectively.