Lung and Intestine: A Specific Link in an Ulcerative Colitis Rat Model
Collagen deposition in the colon and lung of the normal and UC rats (Masson’s trichrome stain, × 40). (a) and (d) The intestinal mucosa and bronchia of the normal rats, only a small amount of collagen tissue. (b) and (e) After TNBS-ethanol enema, collagen fibers increased more than normal group, accompanied with red blood cell exudation and bronchial smooth muscle proliferation. (c) and (f) Four weeks later, a large number of collagen fibers proliferated, even replaced the normal mucosa and glands in the colon and lung tissue.