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Gastroenterology Research and Practice
Volume 2013 (2013), Article ID 264509, 4 pages
Clinical Study

Glossopharyngeal Nerve Block versus Lidocaine Spray to Improve Tolerance in Upper Gastrointestinal Endoscopy

1PEMEX Regional Hospital Salamanca, Subdirección de Servicios de Salud, Gerencia de Servicios Médicos. Av. Tampico 910 Col. Bellavista, 36730 Salamanca, Guanajuato, Mexico
2Division of Health Sciences, Department of Medicine and Nutrition, Campus Leon, University of Guanajuato, 20 de Enero No. 929, Colonia Obregón, 37320 León, Guanajuato, Mexico
3Instituto Mexicano del Seguro Social, Director of Education and Research, UMAE HE 1, Paseo de los Insurgentes SN, Colonia Paraísos, 37150 León, Guanajuato, Mexico
4Universidad De LaSalle Bajío, School of Dentistry, Av. Universidad 602, Col. Lomas del Campestre, 37150 León, Guanajuato, Mexico
5PEMEX Subdirección de Servicios de Salud, Av. Marina Nacional 350 Col. Petroleos Mexicanos, 11311 Distrito Federal, Mexico

Received 5 December 2012; Revised 4 February 2013; Accepted 9 February 2013

Academic Editor: Spiros D. Ladas

Copyright © 2013 Moisés Ortega Ramírez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim of the Study. To compare the effect of glossopharyngeal nerve block with topical anesthesia on the tolerance of patients to upper gastrointestinal endoscopy. Methods. We performed a clinical trial in one hundred patients undergoing upper gastrointestinal endoscopy. Subjects were randomly assigned to one of the following two groups: (1) treatment with bilateral glossopharyngeal nerve block (GFNB) and intravenous midazolam or (2) treatment with topical anesthetic (TASS) and intravenous midazolam. We evaluated sedation, tolerance to the procedure, hemodynamic stability, and adverse symptoms. Results. We studied 46 men and 54 women, from 17 to 78 years of age. The procedure was reported without discomfort in 48 patients (88%) in the GFNB group and 32 (64%) in the TAAS group; 6 patients (12%) in GFNB group and 18 (36%) in TAAS group reported the procedure as little discomfort ( , ). There was no difference in frequency of nausea (4% in both groups) and retching, 4% versus 8% for GFNB and TASS group, respectively ( ). Conclusions. The use of glossopharyngeal nerve block provides greater comfort and tolerance to the patient undergoing upper gastrointestinal endoscopy. It also reduces the need for sedation.