NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding: A Prospective Capsule Endoscopy Study
Table 5
Inflammatory markers in patients with rheumatoid arthritis according to NSAID-induced enteropathy.
Mucosal damage score
N
Mean
SD
Median
1st quartile
3rd quartile
Normality
CRP (mg/L)
No enteropathy
12
21.0
21.8
12.5
2.0
40.5
nn
Any enteropathy
25
17.0
23.0
5.0
1.0
34.0
nn
1
18
10.0
14.4
3.0
1.0
11.0
nn
2
4
19.0
33.1
3.0
0.3
52.3
nn
3
3
57.0
12.1
61.0
43.0
66.0
n
Leu (×109/L)
No enteropathy
12
9.3
3.0
9.9
7.2
11.4
n
Any enteropathy
25
9.2
2.9
8.6
7.2
11.4
n
1
18
9.8
3.2
9.2
77.9
12.6
n
2
4
7.5
1.3
7.4
6.3
8.9
n
3
3
8.1
1.5
7.5
6.8
9.6
n
ESR1
No enteropathy
12
23.0
21.2
15.5
7.0
25.5
nn
Any enteropathy
25
34.0
24.6
26.0
13.0
51.5
nn
1
18
32.0
25.9
23.0
9.5
51.8
nn
2
4
27.0
16.3
24.5
13.0
42.8
n
3
3
52.0
24.0
52.0
28.0
76.0
n
ESR2
No enteropathy
12
41.0
27.4
32.5
18.5
51.3
n
Any enteropathy
25
54.0
30.6
52.0
29.0
78.0
n
1
18
52.0
31.7
53.0
21.8
78.5
n
2
4
46.0
21.6
40.5
29.0
68.5
n
3
3
79.0
30.5
80.0
48.0
109.0
n
Mucosal damage score: 1 mild enteropathy, 2 moderate enteropathy, 3 severe enteropathy, CRP (mg/L): C-reactive protein, Leu (×109/L): leukocytes count, and ESR: sedimentation of erythrocytes after 1 and 2 hours. Normality of data distribution: normal (n) or nonnormal (nn).