Sodium Valproate Inhibits the Growth of Human Cholangiocarcinoma In Vitro and In Vivo
Effects of sodium valproate on cell cycle distribution in cholangiocarcinoma TFK-1 cells and QBC939 cells. (a) TFK-1 cells were incubated with 0–8 mM sodium valproate, and (b) QBC939 cells were incubated with 0–10 mM sodium valproate. On 24 h, 72 h, and 120 h, cells were harvested, and the fractions of cells in G0/G1-phase, S-phase, and G2/M-phase were determined by flow cytometry.
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