The Relation between Obesity and Survival after Surgical Resection of Hepatitis C Virus-Related Hepatocellular Carcinoma

Table 1

Baseline characteristics between the obesity group and the control group.

Variables	Obesity group (𝑛=60)	Control group (𝑛=173)	P value
Age (years)	67.2 ± 8.1	70.2 ± 8.1	0.013^a
Gender: male/female	40/20	119/54	0.872^b
Body mass index (kg/m^2)	27.6 ± 2.6	21.3 ± 2.4	<0.001^a
HCC stage
Stage I/II/III/IV	7/40/11/2	12/45/97/19	0.407^b
Type of hepatectomy
Anatomical; /nonanatomical	15/45	63/110	0.115^b
Maximum tumor size (cm)	3.6 ± 1.6	4.2 ± 2.5	0.087^a
Tumor number, the single/multiple	45/15	117/56	0.331^b
Child-Pugh classification
The Child-Pugh A/B	54/6	158/15	0.795^b
Hepatitis C viral load
High/low/unknown	39/11/10	109/25/39	0.554^b
IFN therapy after surgery: yes/no	5/55	11/162	0.767^b
AST (IU/L)	70.7 ± 42.2	66.5 ± 49.2	0.561^a
ALT (IU/L)	65.6 ±49.7	59.3 ± 42.0	0.342^a
Serum albumin (g/dL)	3.7 ± 0.5	3.8 ± 0.5	0.555^a
Total bilirubin (mg/dL)	0.95 ± 0.47	0.82 ± 0.40	0.043^a
Prothrombin time (%)	87.1 ± 14.0	87.7 ± 13.4	0.756^a
Platelets (×10^4/mm^3)	11.7 ± 5.0	13.4 ± 5.7	0.043^a
ICGR 15	17.6 ± 11.0	14.4 ± 9.1	0.027^a
AFP (ng/mL)	528.6 ± 1870.3	2422.7 ± 13113.3	0.267^a
DCP (mAU/mL)	1505.3 ± 4975.0	3789.9 ± 16524.2	0.293^a
Total cholesterol (IU/L)	170.7 ± 35.0	161.7 ± 33.0	0.083^a
Diabetes mellitus: yes/no	19/41	45/128	0.405^b

Data are expressed as number or mean ± standard deviation. HCC: hepatocellular carcinoma, IFN: interferon, AST: aspartate aminotransferase, ALT: alanine aminotransferase, ICGR 15: indocyanine green retention at 15 min, AFP: alpha-fetoprotein, DCP: des-γ-carboxy prothrombin, ^aunpaired t test, and ^bFisher^,s exact test.