The Relation between Obesity and Survival after Surgical Resection of Hepatitis C Virus-Related Hepatocellular Carcinoma

Table 3

Multivariate analysis associated with OS after surgical resection for hepatocellular carcinoma.

Variable	Hazard ratio	95% confidence interval	P value^a
HCC stage
Stage I or II	1.000		0.069
Stage III or IV	0.423	0.168–1.070
Maximum tumor size
≥3.5 cm	0.765	0.502–1.167	0.214
<3.5 cm	1.000
Tumor number
Single	1.299	0.520–3.244	0.576
Multiple	1.000
IFN therapy after surgery
Yes	3.054	0.745–12.520	0.121
No	1.000
ICGR 15
≥13.5%	0.954	0.623–1.460	0.828
<13.5%	1.000
Serum albumin level
≥3.8 g/dL	1.981	1.295–3.031	0.002
<3.8 g/dL	1.000
AFP level
≥20 ng/mL	0.425	0.274–0.660	<0.001
<20 ng/mL	1.000
Microscopic vascular invasion
Yes	0.549	0.359–0.840	0.006
No	1.000

OS: overall survival, HCC: hepatocellular carcinoma, IFN: interferon, ICGR 15: indocyanine green retention at 15 min, AFP: alpha-fetoprotein, and ^aThe Cox proportional hazard model.