The Relation between Obesity and Survival after Surgical Resection of Hepatitis C Virus-Related Hepatocellular Carcinoma

Table 4

Multivariate analysis associated with RFS after surgical resection for hepatocellular carcinoma.

Variable	Hazard ratio	95% confidence interval	P value^a
HCC stage
Stage I or II	1.000		0.766
Stage III or IV	0.900	0.449–1.802
Tumor number
Single	1.000		0.115
Multiple	0.573	0.287–1.144
IFN therapy after surgery
Yes	2.709	1.264–5.807	0.010
No	1.000
AST
≥60 IU/L	1.091	0.651–1.595	0.933
<60 IU/L	1.000
ALT
≥50 IU/L	0.770	0.489–1.211	0.257
<50 IU/L	1.000
AFP
≥20 ng/mL	0.739	0.522–1.046	0.088
<20 ng/mL	1.000
DCP
≥100 mAU/mL	0.846	0.612–1.170	0.313
<100 mAU/mL	1.000
Microscopic vascular invasion
Yes	0.560	0.397–0.788	0.001
No	1.000

RFS: recurrence-free survival, HCC: hepatocellular carcinoma, IFN: interferon, AST: aspartate aminotransferase, ALT: alanine aminotransferase, AFP: alpha-fetoprotein, DCP: des-γ-carboxy prothrombin, and ^aThe Cox proportional hazard model.