Risk of Atherosclerosis and Helicobacter pylori Infection according to CD14 Promotor Polymorphism in Healthy Korean Population

Table 1

Risk factors of atherosclerosis according to CD 14 −159 genotypes.

	CC	CT	TT	P *
Age	47.00±11.95	47.56±11.43	48.44±10.04	0.75
Sex (male : female)	11 : 10	80 : 40	79 : 46	0.44
Smoking	12	50	42	0.09
Alcohol drinking	14	72	68	0.47
H. pylori infection	14	65	54	0.06
Waist circumference (cm)	87.52±7.97	88.88±8.65	87.79±7.93	0.58
Body mass index (Kg/m^2)	24.11±2.83	24.34±2.99	24.37±2.91	0.94
SBP (mmHg)	125.28±18.59	126.63±13.52	127.07±14.17	0.88
DBP (mmHg)	75.44±12.76	75.32±9.10	76.23±9.87	0.78
Hemoglobin (g/dL)	14.37±1.35	14.68±1.88	14.59±1.60	0.72
ESR	15.27±1.15	12.84±1.04	13.70±1.03	0.76
AST (IU/L)	24.90±9.12	24.54±9.74	23.05±7.06	0.33
ALT (IU/L)	24.07±15.27	28.36±19.11	26.14±14.12	0.41
rGTP (IU/L)	30.81±31.82	42.44±47.29	36.10±33.00	0.31
FBS (mg/dL)	96.24±11.49	102.22±21.71	103.01±25.21	0.45
Uric acid (mg/dL)	5.43±1.34	5.57±1.54	5.33±1.45	0.48
Triglycerides (mg/dL)	105.38 ± 48.85^†	159.04±123.83	160.76±97.53	0.08
Total cholesterol (mg/dL)	191.52±31.01	204.02±39.22	194.77±32.89	0.13
HDL cholesterol (mg/dL)	52.67 ± 15.04^†	45.87±9.61	44.10±9.19	<0.01*
hs-CRP (mg/dL)	0.23±0.23	0.19±0.40	0.21±0.40	0.92
Lp (a)	11.93±9.92	11.74±13.09	15.92±17.52	0.35
Free T4 (ng/dL)	0.98±0.17	1.03±0.15	1.16±0.91	0.23
TSH (μg/mL)	2.14±1.79	1.89±1.97	1.70±2.68	0.20
Ferritin (ng/mL)	133.00±164.03	134.39±88.13	145.43±129.98	0.87

All values are presented as mean ± standard deviation of the mean. *P values were obtained by one-way ANOVA. ^†P values (CC genotype versus CT/TT genotypes) were obtained by Scheffe’s post hoc test after one-way ANOVA (P < 0.05).
H. pylori: Helicobacter pylori, SBP: systolic blood pressure, DBP: diastolic blood pressure, ESR: erythrocyte sedimentation rate, AST: aspartate transaminase, ALT: alanine aminotransferase, FBS: fasting blood sugar, hs-CRP: high-sensitivity C-reactive protein, Lp (a): lipoprotein a, and TSH: thyroid stimulating hormone.