Research Article

The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns: An Experimental Study

Table 1

Mean histopathological tissue damage score and stenosis index values.

Mean ± SDMin–maxMedianP

SI score
 Group I (control)1.09 ± 0.26*0.7–1.61.10.000
 Group II (BAPN)0.79 ± 0.19*0.6–1.10.7
 Group III
 (prednisolone)
1.03 ± 0.38*0.6–1.61.0
 Group IV (Sham)0.44 ± 0.060.4–0.60.4

HDS score
 Group I (control)4.43 ± 1.13*#2.0–5.05.00.000
 Group II (BAPN)1.93 ± 1.02*0.5–3.51.5
 Group III
 (prednisolone)
3.93 ± 1.02*#3.0–5.03.5
 Group IV (Sham)0.00 ± 0.000.0–0.00.0

ANOVA (Tamhane's T2 ).
* P < 0.05 difference with group IV.
#P < 0.05 difference with group II.