Alterations of Blood-Brain Barrier and Associated Factors in Acute Liver Failure
Figure 2
Transmission electron microscopy of mouse brains from D-galactosamine and liposaccharide-induced ALF. (a) Control (×12000 magnification). TJs (arrow) were intact. (b) ALF mouse (×15000 magnification). EC was shrunken, vesicles and vacuoles (small arrows) were present, and TJs (large arrow) were complete. (c) Another ALF mouse (×12000 magnification). The feet of perivascular astroglial cells (AS) were swollen. TJs (arrow) were disrupted. The rectangular area was magnified in the upper right.
