Table 2: Univariate and multivariate analyses of factors affecting perforation in ESD ().

Univariate Multivariate   OR (95% CI) value OR (95% CI) value Age (years) 1.03 (0.98, 1.08) 0.278     Gender          Female 1.00   1.00    Male 1.16 (0.85, 1.60) 0.351     Tumor size (mm) 6.53 (0.80, 53.51) 0.080 13.32 (1.22, 146.02) 0.034 Tumor location          Cecum 13.2 (1.13, 154.92) 0.040 17.22 (1.25, 236.78) 0.033  Right colon 2.20 (0.23, 20.92) 0.493 1.05 (0.04, 11.68) 0.968   Left colon 4.71 (0.45, 49.94) 0.198 5.65 (0.46, 69.08) 0.175   Rectum 1.00   1.00   Macroscopic type          LST-NG 1.00        LST-G 0.38 (0.10, 1.39) 0.143     Histology          Adenocarcinoma 1.00        Adenoma 1.46 (0.41, 5.20) 0.564     Nonlifting sign, (%)          Negative 1.00   1.00    Positive 3.51 (1.65, 9.71) 0.040 5.97 (1.09, 32.63) 0.039 Procedure time 1.01 (0.99, 1.02) 0.352

ESD: endoscopic submucosal dissection; LST-NG: laterally spreading tumors-nongranular type; LST-G: laterally spreading tumors-granular type.