Clinical Study

Improved Outcome of Biliary Atresia with Postoperative High-Dose Steroid

Table 3

Outcome of children receiving high-dose steroid in different time of Kasai operation.

Outcome≤60 days61–90 days>90 daysP value

Jaundice-free 3 months with native liver25/48 (52.1%)59/98 (60.0%)51/107 (47.7%)>0.05
Jaundice-free 6 months with native liver29/48 (60.0%)63/98 (64.3%)52/107 (48.7%)>0.05
Jaundice-free 12 months with native liver31/48 (64.6%)66/98 (67.3%)50/107 (46.7%)>0.05
Incidence of cholangitis in 1 year14/48 (29.2%)23/98 (23.3%)44/107 (41.1%)>0.05
Two-year survival with native liver rates31/47 (65.9%)51/95 (53.7%)49/104 (47.1%)>0.05

Note: (1) Seven children in the high-dose group were lost to follow-up after 12 months and were included in the analysis of the postoperative bilirubin level and incidence of cholangitis but not in the analysis of survival with native liver rates.
(2) Jaundice-free: direct bilirubin <20 µmol/L.
(3) P value > 0.05: no significant difference was found among the different time of Kasai operation groups.