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Gastroenterology Research and Practice
Volume 2013, Article ID 918031, 7 pages
Review Article

Cryptogenic Multifocal Ulcerous Stenosing Enteritis: A Review of the Literature

2nd Department of Internal Medicine-Gastroenterology, Charles University in Praha, Faculty of Medicine at Hradec Králové, University Teaching Hospital, 500 05 Hradec Králové, Czech Republic

Received 1 April 2013; Accepted 21 October 2013

Academic Editor: Antonin Vavrecka

Copyright © 2013 Darina Kohoutová et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is an extremely rare illness characterised by chronic or relapsing subileus status resulting from multiple small intestinal fibrous strictures and multiple shallow ulcers of the small bowel. The etiology is unknown and pathogenesis is not fully understood. Therapy with systemic glucocorticosteroids is the treatment of choice. However, most patients develop corticosteroid dependence. Deep enteroscopy enables precise diagnostic work, possible endoscopic treatment of stenoses; may obviate the need for surgery and prevent excessive small bowel resections.