Clinical Study

VAWCM-Instillation Improves Delayed Primary Fascial Closure of Open Septic Abdomen

Table 1

Patients characteristics for final analysis.

Pooled ()Irrigation ()Control ()

Age, years (range)49 (20–79)47 (20–79)51 (28–77)0.090
Gender (M : F)92 : 4252 : 2140 : 210.482
Primary diagnosis, number (%)
 Postoperative anastomotic leakage without hemorrhage51 (38.1)26 (35.6)25 (41.0)0.524
 Postoperative anastomotic leakage with hemorrhage8 (6.0)5 (6.8)3 (4.9)0.638
 Severe acute pancreatitis41 (30.6)21 (28.8)20 (32.8)0.615
 Perforation of gastric/duodenal/intestine22 (16.4)13 (17.8)9 (14.8)0.635
 Complicated abdominal abscess7 (5.2)5 (6.8)2 (3.3)0.301
 Othera5 (3.7)3 (4.1)2 (3.3)0.585
Classification of OA, number (%)
 Clean OA without adherence (1a)37 (27.6)21 (28.8)14 (23.0)0.445
 Contaminated OA without adherence (1b)59 (44.0)34 (46.5)25 (41.0)0.471
 Clean OA developing adherence (2a)21 (15.7)13 (17.9)8 (13.1)0.457
 Contaminated OA developing adherence (2b)2 (1.5)1 (1.4)1 (1.6)0.705
 OA complicated by fistula formation (3)7 (5.2)4 (5.5)3 (4.9)0.599
APACHE II scoreb, mean (range)13.9 (7–29)14.2 (9–28)13.7 (7–29)0.433

aOther diagnoses included complicated infected hematoma, septic incomplete abortion with traumatized uterus and perforation, acute ileus, and complicated cholecystitis. bAcute physiology score and chronic health evaluation II.
The “1a, 1b, 2a, 2b, 3” are referred to the classification of the patients with septic OA (see [19]).