Clinical Study
Functional Outcomes and Quality of Life after Restorative Proctocolectomy in Paediatric Patients: A Case-Control Study
Table 1
Characteristics of IPAA patients by age. Except where indicated otherwise, data are median (range) or n (%) values.
| | | IPAA childhood () | IPAA adulthood () | |
| | Age, years | 12 (5–16) | 33.5 (29–48) | <0.0001 | | BMI, kg/m2 | 18 (15–23) | 21.5 (17–28) | 0.09 | | Sex (male/female), n | 5/7 | 11/13 | >0.99 | | Steroids at time of first surgery* | 4 (33.3) | 9 (37.5) | >0.99 | | Azathioprine at time of first surgery | 0 (0) | 2 (8.3) | 0.54 | | Naïve to biologic drugs | 2 (16.6) | 13 (54.2) | 0.04 | | Drugs other than anti-UC drugs | 1 (8.3) | 7 (29.2) | 0.2 | | EIMs | 7 (58.3) | 4 (16.7) | 0.02 | | Three-stage procedure | 5 (41.7) | 4 (16.7) | 0.12 | | Hand-sewn anastomosis | 4 (33.3) | 9 (37.5) | >0.99 | | Major perioperative complications | 1 (8.3) | 1 (4.2) | >0.99 | | Pouchitis | | | | | At least one episode | 3 (25) | 3 (12.5) | 0.38 | | Relapsing at least once | 3/3 (100) | 1/3 (33.3) | 0.09 |
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IPAA: ileal-pouch anal anastomosis; BMI: body mass index; UC: ulcerative colitis; EIMs: extraintestinal manifestations.
*>20 mg of corticosteroids.
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